CMap Candidate Details

Structure:
CMap ID: C01950
Pert ID: BRD-A79903587
Compound Name: tegafur
Targets: TYMS
MoA: Thymidylate synthase inhibitor
SMILES: Fc1cn(C2CCCO2)c(=O)[nH]c1=O
InchiKey: WFWLQNSHRPWKFK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24397 BRD-A79903587 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24542 BRD-A79903587 A549 10 uM 24 h 0.0 0.0 0.0 -0.3 -0.99 0.51
24734 BRD-A79903587 HA1E 10 uM 6 h 0.31 1.29 0.64 0.0 0.0 0.0
24856 BRD-A79903587 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25224 BRD-A79903587 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25308 BRD-A79903587 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52733 BRD-A79903587 HEPG2 4 uM 24 h 0.28 1.18 0.39 -0.39 -1.31 1.69
53219 BRD-A79903587 MCF10A 100 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91388 BRD-A79903587 HUH7 15 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).