CMap Candidate Details

Structure:
CMap ID: C19514
Pert ID: BRD-K53734668
Compound Name: BIIB-057
Targets: --
MoA: --
SMILES: N[C@H]1CCCC[C@H]1Nc1ncc(C(N)=O)c(Nc2cccc(c2)-n2nccn2)n1
InchiKey: TXGKRVFSSHPBAJ-JKSUJKDBSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
503 BRD-K53734668 BJAB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
539 BRD-K53734668 HBL1 10 uM 24 h 0.21 0.86 0.01 0.25 0.89 0.2
600 BRD-K53734668 K562 2.5 uM 4 h 0.0 0.0 0.0 -0.36 -1.21 1.24
639 BRD-K53734668 KMS34 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
685 BRD-K53734668 MINO 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
732 BRD-K53734668 NALM6 2.5 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
792 BRD-K53734668 OCILY19 0.66 uM 4 h 0.0 0.0 0.0 0.0 0.0 0.0
812 BRD-K53734668 OCILY3 10 uM 24 h 0.29 1.2 0.42 0.0 0.0 0.0
875 BRD-K53734668 SKMEL5 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
915 BRD-K53734668 THP1 10 uM 24 h 0.0 0.0 0.0 0.23 0.81 0.09
969 BRD-K53734668 TMD8 2.5 uM 4 h 0.0 0.0 0.0 0.0 0.0 0.0
97032 BRD-K53734668 A375 3.33 uM 24 h 0.18 0.76 0.0 -0.21 -0.71 0.03
97110 BRD-K53734668 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).