CMap Candidate Details
Structure:
| CMap ID: | C19523 |
| Pert ID: | BRD-K53765467 |
| Compound Name: | empagliflozin |
| Targets: | SLC5A2 |
| MoA: | Sodium/glucose cotransporter inhibitor |
| SMILES: | OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ccc(O[C@H]3CCOC3)cc2)c1 |
| InchiKey: | OBWASQILIWPZMG-QZMOQZSNSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 121568 | BRD-K53765467 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.28 | -0.94 | 0.38 |
| 121610 | BRD-K53765467 | HA1E | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121686 | BRD-K53765467 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121710 | BRD-K53765467 | YAPC | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.06 | 0.73 |
| 129609 | BRD-K53765467 | HELA | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.03 | 0.62 |
| 129642 | BRD-K53765467 | HT29 | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.31 | 1.1 | 0.69 |
| 129699 | BRD-K53765467 | PC3 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |