CMap Candidate Details

Structure:
CMap ID: C19603
Pert ID: BRD-K53987533
Compound Name: fluphenazine
Targets: DRD1; DRD2
MoA: Dopamine receptor antagonist
SMILES: FC(F)(F)c1ccc2Sc3ccccc3N(CCCN4CCN(CCCl)CC4)c2c1
InchiKey: WHVNGICQKYBDDP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4121 BRD-K53987533 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.2 -0.69 0.02
4579 BRD-K53987533 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4696 BRD-K53987533 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4939 BRD-K53987533 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37173 BRD-K53987533 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37399 BRD-K53987533 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37692 BRD-K53987533 ASC 10 uM 24 h -0.16 -0.68 0.0 -0.28 -0.95 0.4
37922 BRD-K53987533 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.47 -1.59 15.65
38096 BRD-K53987533 HT29 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.94 0.37
38211 BRD-K53987533 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38514 BRD-K53987533 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38747 BRD-K53987533 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38974 BRD-K53987533 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).