CMap Candidate Details

Structure:
CMap ID: C01962
Pert ID: BRD-A80502530
Compound Name: cinobufagin
Targets: ATP1A1
MoA: ATPase inhibitor
SMILES: C[C@@H]1C[C@H]2[C@@H](CC[C@@H]3C[C@@H](O)CC[C@@]32C)[C@]45O[C@@H]5[C@H](OC(=O)C)[C@@H](C14)c6ccc(=O)oc6
InchiKey: XSIZUTIZDQZYMA-SBWPMOMYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2975 BRD-A80502530 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.52 -1.77 15.65
3324 BRD-A80502530 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.43 -1.45 15.35
3452 BRD-A80502530 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3931 BRD-A80502530 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41687 BRD-A80502530 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41890 BRD-A80502530 A549 10 uM 24 h 0.0 0.0 0.0 -0.55 -1.84 15.65
42236 BRD-A80502530 ASC 10 uM 24 h 0.24 1.0 0.11 -0.36 -1.2 1.17
42577 BRD-A80502530 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42882 BRD-A80502530 HT29 10 uM 6 h 0.0 0.0 0.0 -0.49 -1.64 15.65
43271 BRD-A80502530 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.47 -1.57 15.65
43435 BRD-A80502530 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44029 BRD-A80502530 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96067 BRD-A80502530 PHH 3.33 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.81
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).