CMap Candidate Details

Structure:
CMap ID: C19644
Pert ID: BRD-K54095730
Compound Name: CMPD-1
Targets: MAPK14
MoA: P38 MAPK inhibitor
SMILES: Oc1ccc(NC(=O)CCCc2ccc(cc2)-c2ccccc2F)cc1
InchiKey: ODYAQBDIXCVKAE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6892 BRD-K54095730 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7179 BRD-K54095730 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7465 BRD-K54095730 HA1E 10 uM 6 h -0.22 -0.91 0.06 0.31 1.1 0.7
7687 BRD-K54095730 HCC515 10 uM 6 h 0.0 0.0 0.0 0.28 1.0 0.42
7891 BRD-K54095730 HT29 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
8107 BRD-K54095730 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8392 BRD-K54095730 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8704 BRD-K54095730 VCAP 10 uM 24 h 0.19 0.8 0.0 -0.34 -1.15 1.07
99651 BRD-K54095730 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).