CMap Candidate Details

Structure:
CMap ID: C01965
Pert ID: BRD-A80574334
Compound Name: oxalomalic-acid
Targets: IDH1; ACO1
MoA: Isocitrate dehydrogenase inhibitor
SMILES: OC(C(C(O)=O)C(=O)C(O)=O)C(O)=O
InchiKey: YILAUJBAPQXZGM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33736 BRD-A80574334 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34009 BRD-A80574334 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34287 BRD-A80574334 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34523 BRD-A80574334 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34791 BRD-A80574334 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.31 1.1 0.69
35065 BRD-A80574334 HT29 10 uM 6 h 0.25 1.04 0.14 0.26 0.92 0.25
35280 BRD-A80574334 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35702 BRD-A80574334 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35916 BRD-A80574334 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36167 BRD-A80574334 PHH 10 uM 24 h 0.0 0.0 0.0 0.24 0.86 0.16
36460 BRD-A80574334 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36748 BRD-A80574334 VCAP 10 uM 24 h -0.18 -0.75 0.0 0.42 1.49 2.25
96095 BRD-A80574334 A549 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.01
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).