CMap Candidate Details

Structure:
CMap ID: C19676
Pert ID: BRD-K54210043
Compound Name: NS-1619
Targets: KCNMA1
MoA: Calcium channel activator
SMILES: Oc1ccc(cc1n2c(=O)[nH]c3cc(ccc23)C(F)(F)F)C(F)(F)F
InchiKey: YLFMCMWKHSDUCT-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5214 BRD-K54210043 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5466 BRD-K54210043 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5649 BRD-K54210043 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6287 BRD-K54210043 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6568 BRD-K54210043 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.97 0.46
39460 BRD-K54210043 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39714 BRD-K54210043 ASC 10 uM 24 h -0.32 -1.35 0.98 0.0 0.0 0.0
40018 BRD-K54210043 HEPG2 10 uM 6 h -0.26 -1.08 0.29 -0.34 -1.14 1.01
40290 BRD-K54210043 HT29 10 uM 6 h 0.0 0.0 0.0 -0.4 -1.33 1.77
40481 BRD-K54210043 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40828 BRD-K54210043 NEU 10 uM 24 h 0.19 0.79 0.0 0.0 0.0 0.0
41135 BRD-K54210043 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41470 BRD-K54210043 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99653 BRD-K54210043 U2OS 15 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).