CMap Candidate Details

Structure:
CMap ID: C19681
Pert ID: BRD-K54233340
Compound Name: dorsomorphin
Targets: PRKAA1; BMPR1A; BMPR1B
MoA: AMPK inhibitor
SMILES: C(CN1CCCCC1)Oc2ccc(cc2)c3cnc4c(cnn4c3)c5ccncc5
InchiKey: XHBVYDAKJHETMP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5788 BRD-K54233340 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6434 BRD-K54233340 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9444 BRD-K54233340 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9750 BRD-K54233340 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10063 BRD-K54233340 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10536 BRD-K54233340 HCT116 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.31 1.71
10802 BRD-K54233340 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11067 BRD-K54233340 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11283 BRD-K54233340 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11511 BRD-K54233340 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11782 BRD-K54233340 NCIH508 10 uM 6 h 0.0 0.0 0.0 -0.41 -1.39 2.02
12071 BRD-K54233340 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12334 BRD-K54233340 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12611 BRD-K54233340 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12812 BRD-K54233340 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12967 BRD-K54233340 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13297 BRD-K54233340 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44418 BRD-K54233340 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44718 BRD-K54233340 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44989 BRD-K54233340 ASC 10 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.24
46105 BRD-K54233340 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46744 BRD-K54233340 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95981 BRD-K54233340 PHH 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99654 BRD-K54233340 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).