CMap Candidate Details

Structure:
CMap ID: C19705
Pert ID: BRD-K54314721
Compound Name: zolmitriptan
Targets: HTR1A; HTR1B; HTR1D; HTR1F
MoA: Serotonin receptor agonist
SMILES: CN(C)CCc1c[nH]c2ccc(C[C@H]3COC(=O)N3)cc12
InchiKey: ULSDMUVEXKOYBU-ZDUSSCGKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4580 BRD-K54314721 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22019 BRD-K54314721 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22304 BRD-K54314721 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22517 BRD-K54314721 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23087 BRD-K54314721 HEPG2 10 uM 6 h -0.29 -1.2 0.56 0.0 0.0 0.0
23382 BRD-K54314721 HT29 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.09 0.85
23872 BRD-K54314721 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24175 BRD-K54314721 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37693 BRD-K54314721 ASC 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.32 1.71
38240 BRD-K54314721 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.28 0.98 0.39
38515 BRD-K54314721 NPC 10 uM 24 h 0.0 0.0 0.0 -0.41 -1.38 2.02
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).