CMap Candidate Details

Structure:
CMap ID: C19710
Pert ID: BRD-K54330070
Compound Name: SB-202190
Targets: MAPK14
MoA: P38 MAPK inhibitor
SMILES: Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1
InchiKey: QHKYPYXTTXKZST-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3040 BRD-K54330070 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3525 BRD-K54330070 PC3 10 uM 24 h 0.22 0.91 0.03 -0.2 -0.69 0.02
3832 BRD-K54330070 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39145 BRD-K54330070 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39715 BRD-K54330070 ASC 10 uM 24 h -0.27 -1.12 0.38 0.0 0.0 0.0
41471 BRD-K54330070 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99056 BRD-K54330070 NEU 10 uM 6 h -0.22 -0.9 0.04 0.0 0.0 0.0
99239 BRD-K54330070 NPC 10 uM 6 h 0.0 0.0 0.0 0.34 1.19 1.03
99655 BRD-K54330070 U2OS 15 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
115995 BRD-K54330070 A549 1.11 uM 24 h 0.0 0.0 0.0 -0.4 -1.33 1.84
116078 BRD-K54330070 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116120 BRD-K54330070 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116167 BRD-K54330070 HT29 10 uM 24 h 0.21 0.87 0.01 0.0 0.0 0.0
116207 BRD-K54330070 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).