CMap Candidate Details

Structure:
CMap ID: C19770
Pert ID: BRD-K54529596
Compound Name: captopril
Targets: ACE
MoA: Angiotensin converting enzyme inhibitor
SMILES: C[C@H](CS)C(=O)N1CCC[C@H]1C(O)=O
InchiKey: FAKRSMQSSFJEIM-RQJHMYQMSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
50022 BRD-K54529596 A549 10 uM 6 h 0.28 1.17 0.38 0.13 0.48 0.0
50202 BRD-K54529596 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50376 BRD-K54529596 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51278 BRD-K54529596 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51483 BRD-K54529596 PC3 10 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.56
91191 BRD-K54529596 HUH7 15 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).