CMap Candidate Details

Structure:
CMap ID: C01978
Pert ID: BRD-A80960055
Compound Name: celastrol
Targets: --
MoA: --
SMILES: CC1C(=O)C(=O)C=C2C1=CC=C1[C@]2(C)CC[C@]2(C)[C@H]3C[C@](C)(CC[C@@]3(C)CC[C@@]12C)C(O)=O
InchiKey: AQKDBFWJOPNOKZ-HSFLDMIGSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33734 BRD-A80960055 A375 10 uM 6 h -0.28 -1.15 0.44 0.0 0.0 0.0
34011 BRD-A80960055 ASC 10 uM 24 h -0.15 -0.64 0.0 0.0 0.0 0.0
34289 BRD-A80960055 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34526 BRD-A80960055 HCC515 10 uM 6 h -0.28 -1.17 0.48 0.0 0.0 0.0
34794 BRD-A80960055 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35067 BRD-A80960055 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35498 BRD-A80960055 MCF??7.00 10 uM 6 h -0.18 -0.74 0.0 0.0 0.0 0.0
36050 BRD-A80960055 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
36462 BRD-A80960055 SKB 10 uM 24 h -0.23 -0.94 0.08 0.0 0.0 0.0
36938 BRD-A80960055 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
96003 BRD-A80960055 PHH 3.33 uM 24 h 0.0 0.0 0.0 0.38 1.33 1.72
96096 BRD-A80960055 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).