CMap Candidate Details

Structure:
CMap ID: C19797
Pert ID: BRD-K54606188
Compound Name: BRD-K54606188
Targets: --
MoA: --
SMILES: Cc1sc-2c(c1C)C(=N[C@@H](CC(=O)OC(C)(C)C)c1nnc(C)n-21)c1ccc(Cl)cc1
InchiKey: DNVXATUJJDPFDM-KRWDZBQOSA-N
Compound Aliases: JQ1-(+)

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
53 BRD-K54606188 BJAB 2.5 uM 4 h 0.24 1.01 0.12 0.0 0.0 0.0
113 BRD-K54606188 HBL1 10 uM 4 h 0.0 0.0 0.0 0.0 0.0 0.0
125 BRD-K54606188 K562 10 uM 24 h 0.25 1.04 0.16 -0.19 -0.64 0.01
175 BRD-K54606188 KMS34 2.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
351 BRD-K54606188 OCILY3 10 uM 4 h 0.19 0.81 0.0 0.0 0.0 0.0
374 BRD-K54606188 SKMEL5 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.09
405 BRD-K54606188 THP1 0.66 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.17
442 BRD-K54606188 TMD8 0.66 uM 24 h 0.26 1.09 0.22 -0.44 -1.47 15.35
87480 BRD-K54606188 MINO 0.66 uM 24 h 0.2 0.82 0.0 -0.3 -1.01 0.56
87535 BRD-K54606188 NALM6 10 uM 24 h 0.24 1.01 0.12 -0.29 -0.99 0.5
87585 BRD-K54606188 OCILY10 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87637 BRD-K54606188 OCILY19 10 uM 24 h 0.24 0.99 0.1 -0.23 -0.77 0.08
90412 BRD-K54606188 VCAP 0.37 uM 24 h -0.21 -0.86 0.02 -0.41 -1.37 2.02
90621 BRD-K54606188 HCT116 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90667 BRD-K54606188 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.34 1.19 1.02
93645 BRD-K54606188 ASC 3.33 uM 24 h 0.24 1.0 0.11 -0.24 -0.81 0.13
93703 BRD-K54606188 CD34 10 uM 24 h 0.22 0.91 0.04 0.0 0.0 0.0
93751 BRD-K54606188 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93831 BRD-K54606188 HEK293 10 uM 24 h 0.25 1.05 0.17 -0.39 -1.31 1.71
93878 BRD-K54606188 HELA 10 uM 24 h 0.32 1.35 0.92 0.0 0.0 0.0
93986 BRD-K54606188 HUVEC 10 uM 24 h 0.25 1.03 0.13 -0.48 -1.61 15.65
94015 BRD-K54606188 JURKAT 10 uM 24 h 0.21 0.88 0.02 -0.21 -0.71 0.03
94095 BRD-K54606188 NEU 3.33 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.84
94134 BRD-K54606188 NPC 10 uM 24 h -0.2 -0.82 0.0 -0.3 -1.03 0.62
94228 BRD-K54606188 SHSY5Y 10 uM 24 h 0.19 0.8 0.0 -0.23 -0.76 0.07
94279 BRD-K54606188 SKL 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94374 BRD-K54606188 YAPC 10 uM 24 h 0.31 1.29 0.64 0.0 0.0 0.0
97328 BRD-K54606188 HAP1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98052 BRD-K54606188 P1A82 10 uM 24 h 0.26 1.07 0.2 0.0 0.0 0.0
117007 BRD-K54606188 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117044 BRD-K54606188 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117122 BRD-K54606188 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117173 BRD-K54606188 HEPG2 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117218 BRD-K54606188 HT29 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.08
117258 BRD-K54606188 MCF??7.00 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
117295 BRD-K54606188 PC3 0.04 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.13
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).