CMap Candidate Details

Structure:
CMap ID: C19808
Pert ID: BRD-K54640016
Compound Name: WAY-362450
Targets: NR1H4
MoA: FXR agonist
SMILES: CC(C)OC(=O)C1=CN(CC(C)(C)c2c1[nH]c1ccccc21)C(=O)c1ccc(F)c(F)c1
InchiKey: INASOKQDNHHMRE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
90450 BRD-K54640016 HL60 10 uM 2 h 0.0 0.0 0.0 0.0 0.0 0.0
121566 BRD-K54640016 A375 3.33 uM 24 h 0.0 0.0 0.0 -0.18 -0.62 0.0
121608 BRD-K54640016 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129608 BRD-K54640016 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129641 BRD-K54640016 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129664 BRD-K54640016 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129698 BRD-K54640016 PC3 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129732 BRD-K54640016 YAPC 0.74 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.9
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).