CMap Candidate Details

Structure:
CMap ID: C19819
Pert ID: BRD-K54665485
Compound Name: R-59022
Targets: DGKA
MoA: Protein kinase inhibitor; Diacylglycerol kinase inhibitor
SMILES: Cc1nc2sccn2c(=O)c1CCN1CCC(CC1)=C(c1ccccc1)c1ccc(F)cc1
InchiKey: MFVJXLPANKSLLD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6781 BRD-K54665485 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7012 BRD-K54665485 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7343 BRD-K54665485 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7892 BRD-K54665485 HT29 10 uM 24 h 0.21 0.86 0.01 0.32 1.14 0.86
8285 BRD-K54665485 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8393 BRD-K54665485 PC3 10 uM 24 h 0.23 0.98 0.09 0.33 1.15 0.9
8705 BRD-K54665485 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99659 BRD-K54665485 U2OS 10 uM 6 h 0.0 0.0 0.0 0.26 0.91 0.23
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).