CMap Candidate Details

Structure:
CMap ID: C19828
Pert ID: BRD-K54704028
Compound Name: BAY-36-7620
Targets: GRM1
MoA: Glutamate receptor antagonist
SMILES: C=C1C[C@@H]2COC(=O)[C@]2(Cc3ccc4ccccc4c3)C1
InchiKey: CVIRWLJKDBYYOG-MJGOQNOKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2903 BRD-K54704028 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.67
3234 BRD-K54704028 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3633 BRD-K54704028 PC3 10 uM 6 h 0.0 0.0 0.0 -0.34 -1.14 1.03
3834 BRD-K54704028 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41790 BRD-K54704028 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42108 BRD-K54704028 A549 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.06 0.72
42395 BRD-K54704028 ASC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.6
42714 BRD-K54704028 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43015 BRD-K54704028 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43329 BRD-K54704028 MCF??7.00 10 uM 6 h 0.25 1.05 0.16 0.0 0.0 0.0
43883 BRD-K54704028 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44140 BRD-K54704028 SKB 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.79 0.11
98150 BRD-K54704028 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98399 BRD-K54704028 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99660 BRD-K54704028 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).