CMap Candidate Details

Structure:
CMap ID: C19829
Pert ID: BRD-K54708045
Compound Name: nTZDpa
Targets: PPARG
MoA: PPAR receptor agonist
SMILES: OC(=O)c1n(Cc2ccc(Cl)cc2)c2ccc(Cl)cc2c1Sc1ccccc1
InchiKey: VUPOTURDKDMIGQ-UHFFFAOYSA-N
Compound Aliases: ntzdpa

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1759 BRD-K54708045 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.86 0.22
1925 BRD-K54708045 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2167 BRD-K54708045 PC3 10 uM 24 h 0.0 0.0 0.0 0.42 1.49 2.26
2467 BRD-K54708045 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41791 BRD-K54708045 A375 10 uM 6 h -0.31 -1.29 0.77 -0.29 -0.99 0.5
42109 BRD-K54708045 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42396 BRD-K54708045 ASC 10 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.18
42715 BRD-K54708045 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43016 BRD-K54708045 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43330 BRD-K54708045 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.3 1.05 0.58
43581 BRD-K54708045 NPC 10 uM 24 h 0.22 0.9 0.02 -0.2 -0.66 0.01
43884 BRD-K54708045 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44141 BRD-K54708045 SKB 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.65
53246 BRD-K54708045 MCF10A 15 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99661 BRD-K54708045 U2OS 10 uM 6 h 0.0 0.0 0.0 0.22 0.77 0.06
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).