CMap Candidate Details

Structure:
CMap ID: C01983
Pert ID: BRD-A81233518
Compound Name: glycopyrrolate
Targets: CHRM1; CHRM2; CHRM3
MoA: Acetylcholine receptor antagonist
SMILES: C[N+]1(C)CCC(C1)OC(=O)C(O)(C1CCCC1)c1ccccc1
InchiKey: ANGKOCUUWGHLCE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
19221 BRD-A81233518 A549 10 uM 24 h 0.0 0.0 0.0 -0.41 -1.38 2.02
19883 BRD-A81233518 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20213 BRD-A81233518 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24995 BRD-A81233518 MCF??7.00 10 uM 24 h -0.24 -1.01 0.17 0.26 0.92 0.25
25481 BRD-A81233518 VCAP 10 uM 6 h -0.24 -0.98 0.12 -0.35 -1.17 1.11
126455 BRD-A81233518 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126561 BRD-A81233518 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134359 BRD-A81233518 A375 0.01 uM 24 h 0.0 0.0 0.0 0.23 0.82 0.1
134410 BRD-A81233518 HA1E 0.25 uM 24 h 0.27 1.14 0.32 0.33 1.18 0.97
134439 BRD-A81233518 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134475 BRD-A81233518 HT29 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134522 BRD-A81233518 HUVEC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134548 BRD-A81233518 MCF10A 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134634 BRD-A81233518 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134658 BRD-A81233518 YAPC 0.01 uM 24 h 0.24 1.02 0.13 -0.22 -0.75 0.07
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).