CMap Candidate Details

Structure:
CMap ID: C19868
Pert ID: BRD-K54847683
Compound Name: equol
Targets: ESR1; ESR2
MoA: Estrogen receptor agonist
SMILES: Oc1ccc(cc1)[C@H]1COc2cc(O)ccc2C1
InchiKey: ADFCQWZHKCXPAJ-GFCCVEGCSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124277 BRD-K54847683 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124323 BRD-K54847683 HEK293 1.11 uM 24 h 0.0 0.0 0.0 0.36 1.28 1.36
124360 BRD-K54847683 HELA 10 uM 24 h 0.34 1.41 1.03 -0.3 -1.01 0.56
124428 BRD-K54847683 JURKAT 10 uM 24 h -0.23 -0.96 0.1 0.0 0.0 0.0
124454 BRD-K54847683 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124494 BRD-K54847683 MDAMB231 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124523 BRD-K54847683 PC3 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.31
124553 BRD-K54847683 YAPC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132365 BRD-K54847683 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132394 BRD-K54847683 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132468 BRD-K54847683 HT29 0.03 uM 24 h 0.0 0.0 0.0 0.34 1.2 1.13
132529 BRD-K54847683 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132616 BRD-K54847683 THP1 0.03 uM 24 h 0.0 0.0 0.0 -0.27 -0.89 0.27
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).