CMap Candidate Details

Structure:
CMap ID: C00199
Pert ID: BRD-A07875874
Compound Name: cilnidipine
Targets: CACNA1B
MoA: Calcium channel blocker
SMILES: COCCOC(=O)C1=C(C)NC(=C(C1c2cccc(c2)[N+](=O)[O-])C(=O)OCC=Cc3ccccc3)C
InchiKey: KJEBULYHNRNJTE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1476 BRD-A07875874 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1805 BRD-A07875874 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.48
2277 BRD-A07875874 PC3 10 uM 24 h 0.23 0.96 0.08 0.39 1.39 2.17
2759 BRD-A07875874 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41641 BRD-A07875874 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41865 BRD-A07875874 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42168 BRD-A07875874 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42514 BRD-A07875874 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42825 BRD-A07875874 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43107 BRD-A07875874 MCF??7.00 10 uM 24 h -0.21 -0.86 0.02 -0.27 -0.9 0.28
43372 BRD-A07875874 NPC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
43687 BRD-A07875874 PHH 10 uM 24 h -0.22 -0.93 0.07 -0.32 -1.07 0.77
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).