CMap Candidate Details

Structure:
CMap ID: C19929
Pert ID: BRD-K55070890
Compound Name: thiothixene
Targets: HTR2A
MoA: Dopamine receptor antagonist
SMILES: CN(C)S(=O)(=O)c1ccc2Sc3ccccc3C(=CCCN3CCNCC3)c2c1
InchiKey: NIOGWJDNUIUWFG-WSVATBPTSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
19076 BRD-K55070890 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
19306 BRD-K55070890 A549 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.89 0.27
19721 BRD-K55070890 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20045 BRD-K55070890 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20381 BRD-K55070890 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20698 BRD-K55070890 HT29 10 uM 6 h -0.22 -0.94 0.08 0.0 0.0 0.0
21096 BRD-K55070890 MCF??7.00 10 uM 6 h 0.2 0.85 0.0 0.38 1.34 1.72
21471 BRD-K55070890 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
21766 BRD-K55070890 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).