CMap Candidate Details

Structure:
CMap ID: C19947
Pert ID: BRD-K55127134
Compound Name: fluphenazine
Targets: DRD1; DRD2
MoA: Dopamine receptor antagonist
SMILES: OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1
InchiKey: PLDUPXSUYLZYBN-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1132 BRD-K55127134 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7688 BRD-K55127134 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.1 0.86
7893 BRD-K55127134 HT29 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
23088 BRD-K55127134 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.32 1.12 0.77
23595 BRD-K55127134 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.75 0.06
88145 BRD-K55127134 VCAP 20 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.35
90950 BRD-K55127134 HUH7 8 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
109013 BRD-K55127134 U2OS 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
124276 BRD-K55127134 A375 10 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.72
124289 BRD-K55127134 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124305 BRD-K55127134 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124322 BRD-K55127134 HEK293 10 uM 24 h -0.23 -0.95 0.09 0.0 0.0 0.0
124359 BRD-K55127134 HELA 10 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.27
124427 BRD-K55127134 JURKAT 10 uM 24 h -0.23 -0.94 0.08 0.0 0.0 0.0
124453 BRD-K55127134 MCF10A 10 uM 24 h -0.23 -0.97 0.1 0.0 0.0 0.0
124493 BRD-K55127134 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.43 1.51 2.28
124552 BRD-K55127134 YAPC 10 uM 24 h 0.28 1.17 0.37 0.0 0.0 0.0
132615 BRD-K55127134 THP1 0.01 uM 24 h 0.0 0.0 0.0 -0.23 -0.79 0.11
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).