CMap Candidate Details

Structure:
CMap ID: C19966
Pert ID: BRD-K55186349
Compound Name: BRD-K55186349
Targets: APLNR
MoA: Apelin receptor antagonist
SMILES: [O-][N+](=O)c1ccc(cc1)C(=O)Oc1coc(CSc2ncccn2)cc1=O
InchiKey: UASIRTUMPRQVFY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
16476 BRD-K55186349 A375 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.01 0.55
16708 BRD-K55186349 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
17037 BRD-K55186349 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
17375 BRD-K55186349 HEPG2 10 uM 6 h -0.27 -1.11 0.36 -0.39 -1.31 1.69
17713 BRD-K55186349 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
17999 BRD-K55186349 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
18303 BRD-K55186349 PC3 10 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.13
18600 BRD-K55186349 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).