CMap Candidate Details

Structure:
CMap ID: C20007
Pert ID: BRD-K55301415
Compound Name: abiraterone
Targets: CYP17A1
MoA: Androgen biosynthesis inhibitor
SMILES: C[C@]12CC[C@@H]3[C@@H](CC=C4C[C@@H](O)CC[C@@]34C)[C@@H]1CC=C2c1cccnc1
InchiKey: GZOSMCIZMLWJML-CHCBBUOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49862 BRD-K55301415 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50025 BRD-K55301415 A549 10 uM 6 h -0.26 -1.08 0.29 0.0 0.0 0.0
50205 BRD-K55301415 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50555 BRD-K55301415 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50674 BRD-K55301415 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
50847 BRD-K55301415 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51158 BRD-K55301415 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).