CMap Candidate Details

Structure:
CMap ID: C20038
Pert ID: BRD-K55420858
Compound Name: mirin
Targets: MRE11
MoA: MRE11A exonuclease inhibitor
SMILES: NC1=NC(=O)C(S1)=Cc1ccc(O)cc1
InchiKey: YBHQCJILTOVLHD-YVMONPNESA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33696 BRD-K55420858 A375 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.95 0.39
33813 BRD-K55420858 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34127 BRD-K55420858 ASC 10 uM 24 h 0.22 0.9 0.02 0.0 0.0 0.0
34382 BRD-K55420858 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34644 BRD-K55420858 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34911 BRD-K55420858 HEPG2 10 uM 6 h 0.26 1.08 0.21 -0.32 -1.06 0.75
35163 BRD-K55420858 HT29 10 uM 6 h -0.26 -1.1 0.35 0.0 0.0 0.0
35468 BRD-K55420858 MCF??7.00 10 uM 6 h 0.2 0.81 0.0 -0.19 -0.65 0.01
35800 BRD-K55420858 NPC 10 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.34
35969 BRD-K55420858 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36286 BRD-K55420858 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36588 BRD-K55420858 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36837 BRD-K55420858 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).