CMap Candidate Details

Structure:
CMap ID: C20050
Pert ID: BRD-K55454768
Compound Name: TAS-301
Targets: CAMK2A
MoA: Calcium/calmodulin dependent protein kinase inhibitor
SMILES: COc1ccc(cc1)C(=C2C(=O)Nc3ccccc23)c4ccc(OC)cc4
InchiKey: KUEYYIJXBRWZIB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6784 BRD-K55454768 A375 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.12
7015 BRD-K55454768 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7467 BRD-K55454768 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.93 0.34
7690 BRD-K55454768 HCC515 10 uM 6 h 0.0 0.0 0.0 0.28 1.01 0.44
7896 BRD-K55454768 HT29 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.34 1.85
8154 BRD-K55454768 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8395 BRD-K55454768 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8707 BRD-K55454768 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99669 BRD-K55454768 U2OS 10 uM 6 h 0.19 0.79 0.0 0.27 0.96 0.33
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).