CMap Candidate Details

Structure:
CMap ID: C02008
Pert ID: BRD-A82156122
Compound Name: saxagliptin
Targets: DPP4
MoA: Dipeptidyl peptidase inhibitor
SMILES: N[C@H](C(=O)N1[C@@H]2C[C@H]2C[C@H]1C#N)C12CC3CC(CC(O)(C3)C1)C2
InchiKey: QGJUIPDUBHWZPV-BBIKMUCQSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
126392 BRD-A82156122 A549 3.33 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.09
126410 BRD-A82156122 HA1E 0.04 uM 24 h -0.28 -1.18 0.51 0.2 0.71 0.02
126461 BRD-A82156122 HEK293 0.125 uM 24 h 0.23 0.94 0.06 -0.27 -0.92 0.33
126529 BRD-A82156122 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126565 BRD-A82156122 MDAMB231 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.82
126586 BRD-A82156122 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.34 1.21 1.15
134363 BRD-A82156122 A375 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134444 BRD-A82156122 HELA 0.25 uM 24 h -0.29 -1.19 0.55 -0.29 -0.98 0.49
134478 BRD-A82156122 HT29 0.25 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.73
134528 BRD-A82156122 HUVEC 0.25 uM 24 h 0.18 0.75 0.0 0.0 0.0 0.0
134580 BRD-A82156122 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.24
134664 BRD-A82156122 YAPC 0.74 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.13
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).