CMap Candidate Details

Structure:
CMap ID: C02011
Pert ID: BRD-A82307304
Compound Name: atorvastatin
Targets: DPP4; HMGCR
MoA: HMGCR inhibitor
SMILES: CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CCC(O)CC(O)CC(O)=O)-c1ccccc1
InchiKey: XUKUURHRXDUEBC-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1166 BRD-A82307304 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1249 BRD-A82307304 A549 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
1354 BRD-A82307304 U2OS 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
49783 BRD-A82307304 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50124 BRD-A82307304 HA1E 10 uM 6 h 0.0 0.0 0.0 0.34 1.19 1.05
50477 BRD-A82307304 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50817 BRD-A82307304 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
50993 BRD-A82307304 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).