CMap Candidate Details

Structure:
CMap ID: C02013
Pert ID: BRD-A82329351
Compound Name: cycloheximide
Targets: RPL3
MoA: Protein synthesis inhibitor
SMILES: CCOC(=O)CN1C(=O)CC(C[C@@H](O)C2C[C@@H](C)C[C@H](C)C2=O)CC1=O
InchiKey: KWCVNASRVVSXHH-LYUYJPIDSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1710 BRD-A82329351 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2054 BRD-A82329351 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2203 BRD-A82329351 PC3 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
2503 BRD-A82329351 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41688 BRD-A82329351 A375 10 uM 6 h -0.27 -1.11 0.37 0.22 0.77 0.05
42033 BRD-A82329351 A549 10 uM 6 h -0.27 -1.11 0.36 0.0 0.0 0.0
42238 BRD-A82329351 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42579 BRD-A82329351 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42884 BRD-A82329351 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43272 BRD-A82329351 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43436 BRD-A82329351 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43745 BRD-A82329351 PHH 10 uM 24 h -0.3 -1.24 0.67 0.0 0.0 0.0
44031 BRD-A82329351 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100348 BRD-A82329351 U2OS 12.5 uM 6 h 0.0 0.0 0.0 0.3 1.07 0.64
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).