CMap Candidate Details

Structure:
CMap ID: C02016
Pert ID: BRD-A82395837
Compound Name: ginkgolide-b
Targets: GLRA1; GLRB; PTAFR
MoA: Reducing agent; Immunosuppressant; Protease inhibitor; Peptidase inhibitor; GABA receptor antagonist; Glycine receptor antagonist; Platelet activating factor receptor antagonist
SMILES: C[C@H]1C(=O)O[C@H]2[C@@H](O)C34[C@@H]5C[C@@H](C(C)(C)C)C33[C@H](O)C(=O)O[C@H]3O[C@]4(C(=O)O5)[C@@]12O
InchiKey: SQOJOAFXDQDRGF-DJCNAJSISA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
126079 BRD-A82395837 HUVEC 0.04 uM 24 h 0.0 0.0 0.0 -0.4 -1.36 2.02
126124 BRD-A82395837 JURKAT 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126177 BRD-A82395837 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126261 BRD-A82395837 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126296 BRD-A82395837 THP1 1.11 uM 24 h 0.26 1.08 0.22 0.0 0.0 0.0
134005 BRD-A82395837 A375 0.25 uM 24 h 0.25 1.03 0.13 0.24 0.86 0.15
134036 BRD-A82395837 A549 0.03 uM 24 h 0.0 0.0 0.0 -0.28 -0.96 0.42
134064 BRD-A82395837 HA1E 0.25 uM 24 h 0.0 0.0 0.0 0.22 0.77 0.06
134098 BRD-A82395837 HEK293 0.25 uM 24 h 0.0 0.0 0.0 -0.48 -1.62 15.65
134145 BRD-A82395837 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134181 BRD-A82395837 HT29 0.25 uM 24 h -0.25 -1.04 0.22 0.0 0.0 0.0
134227 BRD-A82395837 MCF??7.00 0.03 uM 24 h 0.24 0.99 0.1 0.22 0.78 0.07
134256 BRD-A82395837 MDAMB231 2.22 uM 24 h -0.25 -1.03 0.2 0.0 0.0 0.0
134311 BRD-A82395837 YAPC 2.22 uM 24 h 0.3 1.24 0.53 -0.33 -1.1 0.87
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).