CMap Candidate Details

Structure:
CMap ID: C02019
Pert ID: BRD-A82590476
Compound Name: SDZ-NKT-343
Targets: TACR1
MoA: Tachykinin antagonist
SMILES: CN(Cc1ccccc1)C(=O)C(Cc2ccc3ccccc3c2)NC(=O)C4CCCN4C(=O)Nc5ccccc5[N+](=O)[O-]
InchiKey: PCVSIMQAFWRUEC-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1711 BRD-A82590476 HA1E 10 uM 6 h 0.0 0.0 0.0 0.29 1.03 0.5
2056 BRD-A82590476 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2287 BRD-A82590476 PC3 10 uM 24 h 0.0 0.0 0.0 0.19 0.69 0.01
2623 BRD-A82590476 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39072 BRD-A82590476 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39413 BRD-A82590476 A549 10 uM 6 h 0.22 0.9 0.02 0.0 0.0 0.0
39600 BRD-A82590476 ASC 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.09
39919 BRD-A82590476 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.2 0.73 0.03
40204 BRD-A82590476 HT29 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.3
40440 BRD-A82590476 MCF??7.00 10 uM 24 h 0.21 0.9 0.02 -0.2 -0.68 0.02
40723 BRD-A82590476 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41024 BRD-A82590476 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41347 BRD-A82590476 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100351 BRD-A82590476 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).