CMap Candidate Details

Structure:
CMap ID: C02021
Pert ID: BRD-A82656074
Compound Name: naltrindole
Targets: OPRD1
MoA: Opioid receptor antagonist
SMILES: Oc1ccc2CC3N(CC4CC4)CCC5(C6Oc1c25)C3(O)Cc7c6[nH]c8ccccc78
InchiKey: WIYUZYBFCWCCQJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1517 BRD-A82656074 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2057 BRD-A82656074 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2353 BRD-A82656074 PC3 10 uM 6 h 0.19 0.8 0.0 0.24 0.85 0.14
2604 BRD-A82656074 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39073 BRD-A82656074 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39286 BRD-A82656074 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39601 BRD-A82656074 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39920 BRD-A82656074 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.34 1.19 1.03
40205 BRD-A82656074 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40580 BRD-A82656074 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.2 -0.68 0.02
41025 BRD-A82656074 NPC 10 uM 24 h 0.26 1.1 0.24 0.0 0.0 0.0
41348 BRD-A82656074 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100352 BRD-A82656074 U2OS 10 uM 6 h 0.0 0.0 0.0 0.33 1.16 0.9
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).