CMap Candidate Details

Structure:
CMap ID: C02023
Pert ID: BRD-A82772293
Compound Name: mepazine
Targets: MALT1
MoA: MALT1 inhibitor
SMILES: CN1CCCC(CN2c3ccccc3Sc3ccccc23)C1
InchiKey: CBHCDHNUZWWAPP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
87317 BRD-A82772293 BJAB 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
87341 BRD-A82772293 HBL1 0.125 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.56
87392 BRD-A82772293 K562 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87439 BRD-A82772293 KMS34 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87514 BRD-A82772293 MINO 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
87543 BRD-A82772293 NALM6 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87594 BRD-A82772293 OCILY10 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.33
87643 BRD-A82772293 OCILY19 10 uM 24 h 0.0 0.0 0.0 0.33 1.15 0.9
87695 BRD-A82772293 OCILY3 10 uM 24 h -0.15 -0.63 0.0 0.31 1.09 0.67
87743 BRD-A82772293 SKMEL5 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87814 BRD-A82772293 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
87863 BRD-A82772293 TMD8 10 uM 6 h 0.23 0.95 0.06 0.0 0.0 0.0
125984 BRD-A82772293 A549 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.32
126005 BRD-A82772293 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126054 BRD-A82772293 HT29 10 uM 24 h 0.0 0.0 0.0 0.23 0.83 0.11
126083 BRD-A82772293 HUVEC 10 uM 24 h 0.21 0.87 0.01 0.38 1.36 1.72
126129 BRD-A82772293 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126182 BRD-A82772293 MCF10A 10 uM 24 h 0.28 1.15 0.32 0.27 0.97 0.35
126221 BRD-A82772293 MCF??7.00 3.33 uM 24 h -0.19 -0.78 0.0 0.0 0.0 0.0
126265 BRD-A82772293 PC3 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.24
126341 BRD-A82772293 YAPC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134008 BRD-A82772293 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134103 BRD-A82772293 HEK293 0.25 uM 24 h -0.26 -1.07 0.27 -0.35 -1.18 1.14
134149 BRD-A82772293 HELA 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134259 BRD-A82772293 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.51
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).