CMap Candidate Details

Structure:
CMap ID: C20242
Pert ID: BRD-K56064827
Compound Name: EI-273
Targets: PRKCA; PRKCG
MoA: PKC inhibitor
SMILES: COCc1cc(O)c(O)c(O)c1c2c(O)c(O)c(O)cc2COC
InchiKey: NEBCAMAQXZIVRE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33723 BRD-K56064827 A375 10 uM 6 h -0.3 -1.23 0.64 0.0 0.0 0.0
34128 BRD-K56064827 ASC 10 uM 24 h 0.26 1.07 0.2 -0.29 -0.96 0.44
34383 BRD-K56064827 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34645 BRD-K56064827 HCC515 10 uM 6 h 0.24 0.98 0.09 0.0 0.0 0.0
34912 BRD-K56064827 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.78 0.1
35164 BRD-K56064827 HT29 10 uM 6 h 0.0 0.0 0.0 -0.17 -0.58 0.0
35490 BRD-K56064827 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35584 BRD-K56064827 NEU 10 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.5
35801 BRD-K56064827 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36091 BRD-K56064827 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
36287 BRD-K56064827 PHH 10 uM 24 h -0.22 -0.91 0.06 -0.26 -0.88 0.25
36589 BRD-K56064827 SKB 10 uM 24 h 0.0 0.0 0.0 0.38 1.36 1.72
36978 BRD-K56064827 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
96157 BRD-K56064827 A549 10 uM 24 h 0.21 0.89 0.02 -0.28 -0.95 0.4
99677 BRD-K56064827 U2OS 15 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).