CMap Candidate Details

Structure:
CMap ID: C20292
Pert ID: BRD-K56231354
Compound Name: triprolidine
Targets: HRH1
MoA: Histamine receptor antagonist
SMILES: Cc1ccc(cc1)C(=CCN2CCCC2)c3ccccn3
InchiKey: CBEQULMOCCWAQT-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6787 BRD-K56231354 A375 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
7017 BRD-K56231354 A549 10 uM 24 h 0.23 0.95 0.06 0.0 0.0 0.0
7469 BRD-K56231354 HA1E 10 uM 6 h 0.2 0.84 0.0 0.0 0.0 0.0
8017 BRD-K56231354 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8216 BRD-K56231354 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8396 BRD-K56231354 PC3 10 uM 24 h -0.27 -1.1 0.36 0.0 0.0 0.0
8709 BRD-K56231354 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99679 BRD-K56231354 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).