CMap Candidate Details

Structure:
CMap ID: C20380
Pert ID: BRD-K56478238
Compound Name: P-1075
Targets: KCNJ11
MoA: ATP channel activator; Potassium channel activator
SMILES: CCC(C)(C)NC(=NC#N)Nc1cccnc1
InchiKey: HKZNADVVGXKQDL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
21938 BRD-K56478238 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22308 BRD-K56478238 A549 10 uM 6 h 0.29 1.2 0.42 0.0 0.0 0.0
22520 BRD-K56478238 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22796 BRD-K56478238 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23092 BRD-K56478238 HEPG2 10 uM 6 h -0.23 -0.95 0.09 -0.38 -1.29 1.5
23386 BRD-K56478238 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23598 BRD-K56478238 MCF??7.00 10 uM 24 h 0.28 1.16 0.36 -0.31 -1.05 0.69
23874 BRD-K56478238 PC3 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
24324 BRD-K56478238 VCAP 10 uM 6 h 0.24 1.0 0.11 -0.37 -1.25 1.35
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).