CMap Candidate Details

Structure:
CMap ID: C20387
Pert ID: BRD-K56509348
Compound Name: BMS-182874
Targets: EDNRA
MoA: Endothelin receptor antagonist
SMILES: CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C
InchiKey: MJRGSRRZKSJHOE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6896 BRD-K56509348 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7183 BRD-K56509348 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7472 BRD-K56509348 HA1E 10 uM 6 h -0.21 -0.88 0.03 0.0 0.0 0.0
7695 BRD-K56509348 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.02 0.61
7900 BRD-K56509348 HT29 10 uM 24 h -0.25 -1.05 0.24 -0.16 -0.53 0.0
8108 BRD-K56509348 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8524 BRD-K56509348 PC3 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.18 1.14
8836 BRD-K56509348 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99681 BRD-K56509348 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).