CMap Candidate Details

Structure:
CMap ID: C20388
Pert ID: BRD-K56515112
Compound Name: medrysone
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: C[C@H]1C[C@H]2[C@@H]3CC[C@H](C(=O)C)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]4(C)CCC(=O)C=C14
InchiKey: GZENKSODFLBBHQ-XVDJYXIYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2906 BRD-K56515112 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3237 BRD-K56515112 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.22
3634 BRD-K56515112 PC3 10 uM 6 h -0.25 -1.03 0.2 0.0 0.0 0.0
3973 BRD-K56515112 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.09 0.84
41793 BRD-K56515112 A375 10 uM 6 h -0.17 -0.72 0.0 0.28 0.98 0.37
41952 BRD-K56515112 A549 10 uM 24 h 0.32 1.32 0.82 0.0 0.0 0.0
42399 BRD-K56515112 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42718 BRD-K56515112 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.35 1.25 1.29
43018 BRD-K56515112 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43206 BRD-K56515112 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43887 BRD-K56515112 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99682 BRD-K56515112 U2OS 6.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).