CMap Candidate Details

Structure:
CMap ID: C00204
Pert ID: BRD-A07986123
Compound Name: galeterone
Targets: CYP17A1; AR
MoA: Androgen receptor modulator
SMILES: C[C@]12CCC3C(CC=C4C[C@@H](O)CC[C@]34C)C1CC=C2n1cnc2ccccc12
InchiKey: PAFKTGFSEFKSQG-BLYLLKCRSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
97243 BRD-A07986123 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121140 BRD-A07986123 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121174 BRD-A07986123 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121210 BRD-A07986123 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.7
121245 BRD-A07986123 HELA 10 uM 24 h -0.21 -0.88 0.03 -0.27 -0.92 0.33
121274 BRD-A07986123 HT29 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
121284 BRD-A07986123 MCF??7.00 10 uM 24 h -0.29 -1.2 0.57 0.0 0.0 0.0
121338 BRD-A07986123 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).