CMap Candidate Details

Structure:
CMap ID: C20441
Pert ID: BRD-K56658166
Compound Name: BRD-K56658166
Targets: CACNA1B
MoA: Sodium channel blocker; Calcium channel blocker
SMILES: Brc1ccccc1OCC(=O)NCCc2nc3ccccc3[nH]2
InchiKey: XWFRNTHGPRGCNS-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
13998 BRD-K56658166 A375 10 uM 6 h 0.24 1.01 0.12 0.0 0.0 0.0
14136 BRD-K56658166 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
14480 BRD-K56658166 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
15082 BRD-K56658166 HT29 10 uM 24 h 0.19 0.81 0.0 0.0 0.0 0.0
15358 BRD-K56658166 MCF??7.00 10 uM 24 h -0.21 -0.87 0.02 0.28 1.0 0.43
15638 BRD-K56658166 PC3 10 uM 24 h 0.0 0.0 0.0 0.23 0.82 0.1
15960 BRD-K56658166 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115131 BRD-K56658166 U2OS 20 uM 6 h 0.0 0.0 0.0 -0.19 -0.65 0.01
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).