CMap Candidate Details

Structure:
CMap ID: C02045
Pert ID: BRD-A83855350
Compound Name: naltrexone
Targets: OPRD1; OPRK1; OPRM1
MoA: Opioid receptor antagonist
SMILES: Oc1ccc2CC3N(CC4CC4)CCC5(C6Oc1c25)C3(O)CCC6=O
InchiKey: DQCKKXVULJGBQN-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6702 BRD-A83855350 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6960 BRD-A83855350 A549 10 uM 24 h -0.26 -1.09 0.33 -0.25 -0.83 0.16
7274 BRD-A83855350 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7975 BRD-A83855350 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8278 BRD-A83855350 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8335 BRD-A83855350 PC3 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
8784 BRD-A83855350 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
100355 BRD-A83855350 U2OS 10 uM 6 h 0.0 0.0 0.0 0.25 0.9 0.22
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).