CMap Candidate Details

Structure:
CMap ID: C02047
Pert ID: BRD-A83892713
Compound Name: rifampicin
Targets: NR1I2
MoA: RNA polymerase inhibitor
SMILES: CO[C@H]1C=CO[C@@]2(C)Oc3c(C2=O)c2c(O)c(C=NN4CCN(C)CC4)c(NC(=O)C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(O)c2c(O)c3C
InchiKey: JQXXHWHPUNPDRT-YOPQJBRCSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49785 BRD-A83892713 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
49963 BRD-A83892713 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50126 BRD-A83892713 HA1E 10 uM 6 h 0.22 0.9 0.02 0.0 0.0 0.0
50317 BRD-A83892713 HCC515 10 uM 6 h 0.0 0.0 0.0 0.33 1.18 0.98
50479 BRD-A83892713 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50723 BRD-A83892713 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.1 0.86
50818 BRD-A83892713 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
50994 BRD-A83892713 VCAP 10 uM 24 h 0.26 1.09 0.23 0.0 0.0 0.0
90767 BRD-A83892713 HPTEC 100 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.52
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).