CMap Candidate Details

Structure:
CMap ID: C02048
Pert ID: BRD-A83937277
Compound Name: mephenytoin
Targets: SCN5A
MoA: Hydantoin antiepileptic
SMILES: CCC1(NC(=O)N(C)C1=O)c1ccccc1
InchiKey: GMHKMTDVRCWUDX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6703 BRD-A83937277 A375 10 uM 24 h -0.21 -0.87 0.02 0.0 0.0 0.0
7122 BRD-A83937277 A549 10 uM 6 h 0.25 1.05 0.17 0.0 0.0 0.0
7275 BRD-A83937277 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.3 -0.99 0.51
7814 BRD-A83937277 HT29 10 uM 24 h -0.26 -1.06 0.26 -0.28 -0.93 0.35
8629 BRD-A83937277 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52109 BRD-A83937277 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91081 BRD-A83937277 HUH7 15 uM 72 h 0.23 0.97 0.08 0.0 0.0 0.0
96397 BRD-A83937277 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).