CMap Candidate Details

Structure:
CMap ID: C20481
Pert ID: BRD-K56800335
Compound Name: guanaben-acetate
Targets: ADRA2A; ADRA2B
MoA: Adrenergic receptor agonist
SMILES: NC(=N)NN=C/c1c(Cl)cccc1Cl
InchiKey: WDZVGELJXXEGPV-PQMHYQBVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6788 BRD-K56800335 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8837 BRD-K56800335 VCAP 10 uM 6 h 0.0 0.0 0.0 0.27 0.97 0.34
123832 BRD-K56800335 A549 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.51
123892 BRD-K56800335 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123940 BRD-K56800335 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123992 BRD-K56800335 JURKAT 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124046 BRD-K56800335 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.12
124091 BRD-K56800335 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124119 BRD-K56800335 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124174 BRD-K56800335 THP1 1.11 uM 24 h 0.0 0.0 0.0 0.27 0.96 0.33
124227 BRD-K56800335 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132161 BRD-K56800335 HA1E 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132223 BRD-K56800335 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132293 BRD-K56800335 PC3 0.03 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).