CMap Candidate Details

Structure:
CMap ID: C20485
Pert ID: BRD-K56810756
Compound Name: fomepizole
Targets: ADH1A; ADH1B; ADH1C
MoA: Alcohol dehydrogenase inhibitor
SMILES: Cc1cn[nH]c1
InchiKey: RIKMMFOAQPJVMX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123792 BRD-K56810756 A375 0.04 uM 24 h 0.2 0.83 0.0 -0.26 -0.87 0.24
123834 BRD-K56810756 A549 0.125 uM 24 h 0.2 0.82 0.0 -0.29 -0.98 0.48
123896 BRD-K56810756 HEK293 10 uM 24 h 0.0 0.0 0.0 0.22 0.77 0.06
123996 BRD-K56810756 JURKAT 0.37 uM 24 h 0.23 0.95 0.06 -0.34 -1.14 1.01
124049 BRD-K56810756 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124093 BRD-K56810756 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124120 BRD-K56810756 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124178 BRD-K56810756 THP1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124231 BRD-K56810756 YAPC 1.11 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.85
132164 BRD-K56810756 HA1E 0.08 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
132194 BRD-K56810756 HELA 0.08 uM 24 h 0.37 1.56 1.48 0.0 0.0 0.0
132226 BRD-K56810756 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132295 BRD-K56810756 PC3 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).