CMap Candidate Details
Structure:
| CMap ID: | C20602 |
| Pert ID: | BRD-K57139258 |
| Compound Name: | z-guggulsterone |
| Targets: | NR1H4 |
| MoA: | FXR antagonist; Progesterone receptor agonist |
| SMILES: | CC=C1C(=O)C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C |
| InchiKey: | WDXRGPWQVHZTQJ-AUKWTSKRSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 99060 | BRD-K57139258 | NEU | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.3 | 1.07 | 0.64 |
| 99163 | BRD-K57139258 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.28 | 1.46 |