CMap Candidate Details

Structure:
CMap ID: C20643
Pert ID: BRD-K57252450
Compound Name: cilengitide
Targets: ITGAV; ITGB3
MoA: Integrin inhibitor
SMILES: CC(C)[C@@H]1N(C)C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O
InchiKey: AMLYAMJWYAIXIA-VWNVYAMZSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95509 BRD-K57252450 A549 10 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
95601 BRD-K57252450 MCF??7.00 10 uM 6 h -0.37 -1.53 1.43 -0.33 -1.1 0.87
95621 BRD-K57252450 U2OS 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.01
97294 BRD-K57252450 HAP1 3.33 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.17
123514 BRD-K57252450 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123532 BRD-K57252450 HA1E 10 uM 24 h -0.23 -0.97 0.11 -0.32 -1.06 0.74
123559 BRD-K57252450 HEK293 10 uM 24 h -0.26 -1.07 0.27 0.0 0.0 0.0
123611 BRD-K57252450 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123638 BRD-K57252450 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123677 BRD-K57252450 MCF10A 10 uM 24 h 0.25 1.04 0.14 0.0 0.0 0.0
123739 BRD-K57252450 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123758 BRD-K57252450 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).