CMap Candidate Details

Structure:
CMap ID: C20653
Pert ID: BRD-K57282030
Compound Name: JW-7-24-1
Targets: --
MoA: --
SMILES: COc1cc(OC)cc(c1)-c1ccc2ncc3ccc(=O)n(-c4ccc(N5CCNCC5)c(c4)C(F)(F)F)c3c2c1
InchiKey: VVTHOUCIAGHQBD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91658 BRD-K57282030 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.57
92400 BRD-K57282030 A375 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92427 BRD-K57282030 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92451 BRD-K57282030 BT20 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92489 BRD-K57282030 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.7
92553 BRD-K57282030 HME1 10 uM 3 h 0.32 1.35 0.96 0.0 0.0 0.0
92575 BRD-K57282030 HS578T 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92620 BRD-K57282030 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92691 BRD-K57282030 LNCAP 1.11 uM 3 h 0.0 0.0 0.0 -0.29 -0.96 0.44
92721 BRD-K57282030 MCF10A 0.12 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
92765 BRD-K57282030 MDAMB231 1.11 uM 24 h -0.26 -1.09 0.32 0.0 0.0 0.0
92797 BRD-K57282030 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92844 BRD-K57282030 SKBR3 10 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).