CMap Candidate Details

Structure:
CMap ID: C20659
Pert ID: BRD-K57304726
Compound Name: PRE-084
Targets: SIGMAR1
MoA: Sigma receptor agonist
SMILES: O=C(OCCN1CCOCC1)C1(CCCCC1)c1ccccc1
InchiKey: RQHKZUBCUZVZEF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5344 BRD-K57304726 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5653 BRD-K57304726 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.82
5932 BRD-K57304726 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.98 0.47
6040 BRD-K57304726 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6288 BRD-K57304726 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6573 BRD-K57304726 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.19 -0.65 0.01
37177 BRD-K57304726 A375 10 uM 6 h 0.0 0.0 0.0 0.37 1.31 1.59
37403 BRD-K57304726 A549 10 uM 6 h -0.34 -1.41 1.41 0.0 0.0 0.0
37700 BRD-K57304726 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38212 BRD-K57304726 MCF??7.00 10 uM 24 h -0.27 -1.12 0.38 0.0 0.0 0.0
38521 BRD-K57304726 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38978 BRD-K57304726 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99692 BRD-K57304726 U2OS 10 uM 6 h 0.0 0.0 0.0 0.26 0.92 0.25
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).